Title Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules
نویسندگان
چکیده
Author(s) Sakai, Ryoko; Tanaka, Michi; Nanki, Toshihiro; Watanabe, Kaori; Yamazaki, Hayato; Koike, Ryuji; Nagasawa, Hayato; Amano, Koichi; Saito, Kazuyoshi; Tanaka, Yoshiya; Ito, Satoshi; Sumida, Takayuki; Ihata, Atsushi; Ishigatsubo, Yoshiaki; Atsumi, Tatsuya; Koike, Takao; Nakajima, Atsuo; Tamura, Naoto; Fujii, Takao; Dobashi, Hiroaki; Tohma, Shigeto; Sugihara, Takahiko; Ueki, Yukitaka; Hashiramoto, Akira; Kawakami, Atsushi; Hagino, Noboru; Miyasaka, Nobuyuki; Harigai, Masayoshi
منابع مشابه
Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules.
OBJECTIVE To compare reasons for discontinuation and drug retention rates per reason among anticytokine therapies, infliximab, etanercept and tocilizumab, and the risk of discontinuation of biological agents due to adverse events (AE) in patients with rheumatoid arthritis (RA). METHOD This prospective cohort study included Japanese RA patients who started infliximab (n=412, 636.0 patient-year...
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OBJECTIVE Tumor necrosis factor (TNF) inhibitors have revolutionized the treatment of severe rheumatoid arthritis (RA), yet drug discontinuation is common. The aim of this study was to compare treatment retention rates and specific causes of anti-TNF discontinuation in a population-based RA cohort. METHODS All patients treated with etanercept, infliximab, or adalimumab within the Swiss Clinic...
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